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Cancer Therapies

Phase I Clinical Trial Results Reported

Published in Cancer Weekly, June 1st, 1998

Onyx Pharmaceuticals, Inc., Richmond, California, reported results of two Phase I safety trials of its lead anticancer viral therapeutic, ONYX-015, in pancreatic cancer and in gastrointestinal cancers that have metastasized to the liver.

In both studies, ONYX-015 was found to be safe and well-tolerated, as well as biologically active in the pancreatic study. Based on these results, Onyx is planning to initiate further studies in both cancer types using novel routes of administration and regimens, including combining ONYX-015 with standard chemotherapy.

Results of the two studies were presented at the American Society of Clinical Oncology (ASCO)...

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