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Pancreatic Cancer

RFS 2000 Shows 63 percent Response or Stable Disease in Patients

Published in Cancer Weekly, June 8th, 1998

SuperGen, Inc., San Ramon, California, announced updated interim results from an ongoing Phase II trial of its proprietary drug RFS 2000 for the treatment of pancreatic cancer.

RFS 2000 is a second-generation topoisomerase I inhibitor, which causes single-strand breaks in DNA. Median survival to date is 16.2 months among responders, which is the longest survival rate ever reported among pancreatic cancer patients.

Among stable patients, median survival was 9.7 months and among non-responders, 5.9 months. Data shows that among 61 evaluable patients, 33 percent were responders, 30 percent were stable and 37 percent were non-responders following...

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