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Angiogenesis

Inhibitor Expanded Studies Initiated in Europe and U.S.

Published in Cancer Weekly, June 29th, 1998

Sugen, Inc., Redwood City, California, announced that it is initiating two new clinical studies of its angiogenesis inhibitor, SU5416 in the United States and Europe.

The first of these trials, a Phase I/II study, is conducted by Ian Judson, M.D., Cancer Research Campaign (CRC) Center for Cancer Therapeutics at the Institute for Cancer Research (ICR) and the Royal Marsden Hospital (RMH) in London, United Kingdom.

The study includes up to 24 patients and assesses leakiness of tumor blood vessels as a biological marker for the angiogenic process in addition to monitoring safety and pharmacokinetic parameters for SU5416. Professor Paul Workman, Ph.D.,...

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