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Treatment (Gliomas)

Shark Liver Extract May Work Against Brain Tumors

Published in Cancer Weekly, August 10th, 1998

A chemical taken from shark livers can block the growth of brain tumors in rats, literally starving them of blood, researchers said.

The chemical, known as squalamine, "dramatically" reduces the growth of blood vessels that feed such tumors, researchers at Johns Hopkins University, Cambridge, Massachusetts, said.

Squalamine is being developed by Magainin Pharmaceuticals Inc., Plymouth Meeting, Pennsylvania.

The researchers found that squalamine slowed the growth of brain tumors known as gliomas by 75 percent when the tumors were implanted in the sides of laboratory rats.

"Our results suggest that squalamine may...

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