Cancer Hormone Therapy

Novel Liver Steroid Slows Angiogenesis

Published in Cancer Weekly, August 10th, 1998

Laboratory studies at Johns Hopkins University have dramatically confirmed the power of a chemical discovered from the liver of sharks to slow the formation of new blood vessels destined to feed brain cancers as well as other tumors.

Squalamine, previously shown to have antibiotic and anti-cancer activity, inhibited the growth of brain cancers called gliomas implanted in the flanks of rats by disabling blood vessel growth, or angiogenesis, reported the authors of the studies, published in the July 1, 1998, issue of the journal Cancer Research.

"Our results suggest that squalamine may be well suited for humans in the treatment of brain tumors and...

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Source: Cancer Weekly (1998-08-10)

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