Cytokine Gene Therapy
'Cracked' Adenoproducer Cells Used in Cancer Gene Therapy Approach
Published in Cancer Weekly, August 24th, 1998
M.C. Esandi and colleagues from Leiden University, IntroGene BV, and Pathologisch Laboratorium, The Netherlands, established a new method of anticancer cytokine gene therapy using lysed adenoproducer cells ("IL-1/IL-3 Gene Therapy of Non-Small Cell Lung Cancer (NSCLC) in Rats Using 'Cracked' Adenoproducer Cells," Gene Therapy, June 1998;5(6):778-88).
"In this study, we explored the potential of the cytokines interleukin (IL)-1(alpha) and IL-3(beta) to trigger a systemic antitumor response," stated Esandi et al. "We have been able to induce...
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Source: Cancer Weekly (1998-08-24)
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