Published in Cancer Weekly, September 7th, 1998
Drug resistance is a major obstacle in cancer treatment and is associated with treatment failure. One of the mechanisms of multidrug resistance (MDR) involves the overexpression of the mdr1 gene product, P-glycoprotein (P-gp). Several strategies have been developed to eradicate MDR in P-gp-expressing cells.
Sayuri Motomura and colleagues from the Tokyo Women's Medical College; The Japanese Red Cross Center, The Research Institute of Tuberculosis; the University of...
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