Published in Cancer Weekly, November 23rd, 1998
The advancement of gene transfer technologies has created new therapeutic avenues for stimulating anti-tumor immune responses in patients. In previous research using murine models, G. Dranoff et al. have demonstrated that vaccination with irradiated tumor cells that have been modified ex vivo to secrete GM-CSF can stimulate potent, specific, and long-lasting antitumor immunity in treated animals (PNAS,...
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