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Breast Cancer

"CYP17 Genotype and Breast Cancer Risk."

Published in Cancer Weekly, December 7th, 1998

According to the authors' abstract of an article published in Cancer Epidemiology Biomarkers & Prevention, "The MspAI polymorphism in the 5' untranslated region of CYP17 has been evaluated as a breast cancer risk factor in a hospital-based, case-control study in New York City. The study population consisted of 363 women [123 breast cancer patients and 240 patient controls (123 benign breast disease without atypical hyperplasia, 117 women without breast disease)]. There were 224 Caucasians (76 cases, 148 controls), 55 African-Americans (20 cases, 35 controls), and 84 Hispanics (27 cases, 57 controls), 142 pre-menopausal women, and 221 post-menopausal women. Consistent with a previous...

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