Published in Cancer Weekly, December 7th, 1998
Although several targeted gene therapy strategies have been developed for a number of epithelial malignancies (S.A. Rosenberg et al., Hum Gene Ther., 1996;7:2287-313), these strategies have not been explored in the context of carcinoma of the cervix. Several factors, however, suggest that cervical cancer may be a good candidate for a suicide gene therapy approach.
Matthew W. Robertson III and colleagues from the University of Alabama suggested that the limitations for applying molecular chemotherapy strategies to cervical carcinoma have...
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