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Cancer Immunotherapy

Early Results of INF-(alpha) for Renal Carcinoma are Mixed

Published in Cancer Weekly, February 22nd, 1999

Benefits of subcutaneous administration of interferon alpha (INF-(alpha)) for metastatic renal carcinoma need to be balanced with the risks.

A. Ritchie and colleagues from the Cancer Trials Office, England, reported early clinical trial results of IFN-(alpha) for the treatment of metastatic renal carcinoma ("Interferon-Alpha and Survival in Metastatic Renal Carcinoma: Early Results of a Randomized Controlled Trial," Lancet, January 2, 1999;353(9146):14-17).

"Metastatic renal carcinoma has a 2-year survival of around 20 percent and is largely resistant to chemotherapy," wrote Ritchie et al. "The use of interferons in the treatment of metastatic...

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