Radioimmunotherapy
Alpha-Emitting Antibodies are Safe In Vivo
Published in Cancer Weekly, March 8th, 1999
T.K. Nikula and colleagues from the Memorial Sloan Kettering Cancer Center, New York, described the pharmacokinetic, bioactivity, toxicity and chemical characteristics of cr-particle-emitting, Bi-213 and Bi-212 radiometal conjugated HuM195 (anti-CD33) constructs ("Alpha-Emitting Bismuth Cyclohexylbenzyl DTPA"Alpha-Emitting Bismuth Cyclohexylbenzyl DTPA Constructs of Recombinant Humanized Anti-CD33 Antibodies: Pharmacokinetics, Bioactivity, Toxicity and Chemistry," Journal of Nuclear Medicine, January 1999;40(1):166-176).
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Source: Cancer Weekly (1999-03-08)
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