"Angiogenesis: An Achilles Heel of Solid Tumors?."

According to an abstract submitted by the authors to the Second International Congress 'Biliopancreatic Malignancy: From Gene to Cure,' held February 4-6, 1999, in Amsterdam, The Netherlands, "Many solid tumors depend on an extensive vascular network to become nourished and to grow. They induce the formation of a rich vascular network by the secretion of angiogenic growth factors, that induce the formation new capillary structures when applied to endothelial cells in the proper context. From understanding this context and the response of endothelial cells to tumor-derived angiogenic stimuli new strategies are developed aiming at reducing or curing solid tumors by interfering with their...

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