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Animal Models

TNP-470 Inhibits Hemangioma Development

Published in Cancer Weekly, July 12th, 1999

Researchers have developed an animal model for hemangiomas that may be helpful in studying anti-angiogenesis.

Hemangiomas are the most frequent tumors of infancy. The pathogenesis of these tumors is not well understood, and current treatment of juvenile hemangiomas remains unsatisfactory.

Sandra Liekens and colleagues of Belgium's Rega Institute for Medical Research, University Hospitals, reported on a novel animal model to study proliferating hemangiomas and to evaluate the effect of angiostatic compounds on their growth ("A Novel Animal Model for Hemangiomas: Inhibition of Hemangioma Development by the Angiogenesis Inhibitor TNP-470," Cancer Res,...

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