"The Role of Laminin-1 in the Modulation of Radiation Damage in Endothelial Cells and Differentiation."

According to the authors' abstract of an article published in Radiation Research, "Microvascular dysfunction due to endothelial damage is often associated with the ionizing radiation used during cancer therapy. This radiation-induced capillary injury is a major factor in the inhibition of new vessel growth (angiogenesis) and in disease states such as radiation-induced pneumonitis and nephropathy. Many studies have examined the effects of radiation on endothelial cell function; however, little is known regarding the role the basement membrane plays in radiation-induced endothelial cell damage and angiogenesis. Therefore, we examined the effects of gamma radiation on aortic explants, and...

Want to see the full article?

• Purchase this article for only $3.00