Cancer Gene Therapy

Src Kinase Inhibitor Restricts Leukemic Cell Growth

Published in Cancer Weekly, August 23rd, 1999

A study suggests that Src kinase inhibitors should enter multidrug regimens against myeloid leukemia.

V. Roginskaya and colleagues from the Children's Hospital of Pittsburgh, Pennsylvania, investigated therapeutic targeting of Src-kinase Lyn in myeloid leukemic cell growth. Their study results were published in the journal Leukemia ("Therapeutic Targeting of Src-Kinase Lyn in Myeloid Leukemic Cell Growth," Leukemia, June 1999;13(6):855-861).

"Protein tyrosine kinases play a major role in promoting cell growth, and their activity in solid tumors is well established," wrote Roginskaya et al. "Inhibitors of protein tyrosine kinases are now in advanced...

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Source: Cancer Weekly (1999-08-23)

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