Published in Cancer Weekly, August 30th, 1999
Morphine and hydromorphone, a semi-synthetic derivative of morphine, have similar chemical structures, and pharmacodynamic and pharmacokinetic qualities. Mary G. Miller, MD, MRCP, of Churchill Hospital, Oxford, England, and associates compared these opioids in 74 terminally ill patients ("Continuous Subcutaneous Infusion of Morphine Versus Hydromorphone: A Controlled Trial," Journal of Pain and Symptom Management, July 1999;18(1):9-16).
Those patients who were able to do so completed a pain assessment. For those incapable of doing so, a tool...
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