Published in Cancer Weekly, September 20th, 1999
Tumor progression results from complex interactions between tumor and tumor-associated host issue. Basic fibroblast growth factor (bFGF), by way of activation of its receptor, FGFR-1, has been suggested to be an important inducer of host stromal response and angiogenesis.
Francesca Guddo and colleagues, University of Pisa, Italy, performed a study to assess the putative role of tumor-associated stromal cells and vessels in tumor progression ("The Expression of Basic...
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