CML Gene Therapy
"Antisense Drug Resistant Gene Therapy for CML."
Published in Cancer Weekly, October 11th, 1999
Grant Number: 5R01CA74887-03. Grant Expires: June 30, 2001. Principle Investigator: Catherine M. Verfaillie. Performing Organization: University of Minnesota Twin Cities, Minneapolis, Minnesota 55455. Description: "CML is a malignant disease of the hematopoietic stem cell (HSC) characterized by the BCR/ABL gene rearrangement. The only curative treatment for most patients with CML is transplantation of HSC from an allogeneic donor. Although transplantation of autologous, unpurged or purged bone marrow or blood progenitors can restore Ph-hematopoiesis in some patients, most patients relapse within a year after transplant due in part to...
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Source: Cancer Weekly (1999-10-11)
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