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Breast Cancer (Recurrence)

Cancer Relapse Rates Appear Higher in Women with BRCA Gene

Published in Cancer Weekly, October 11th, 1999

Women with cancer-causing genes who choose lumpectomy and radiation therapy appear to have an increased risk of getting a second tumor in the treated breast five to 10 years after treatment, a Yale study has found.

The results of this 14-year study, appearing in the Journal of Clinical Oncology's October 1999 issue, suggest that breast cancer patients who carry either the BRCA1 or BRCA2 gene may be at higher risk for late relapses than their counterparts who do not harbor these mutations.

"Previous studies have established that women with BRCA1 or BRCA2 genes have a very high rate of developing breast cancer," said Bruce G. Haffty, MD, associate...

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