Published in Cancer Weekly, October 11th, 1999
M. Elkin and colleagues at Israel's Hadassah-Hebrew University Hospital previously demonstrated that halofuginone, a widely-used alkaloid coccidiostat, is a potent inhibitor of collagen (alpha)1(I) and matrix metalloproteinase 2 gene expression. Halofuginone also suppresses extracellular matrix deposition and cell proliferation.
More recently, Elkin et al. investigated the effect of halofuginone on transplantable and chemically-induced mouse bladder carcinoma ("Inhibition of Bladder Carcinoma...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.