Published in Cancer Weekly, October 11th, 1999
Studies have shown that the presence of an eosinophilic infiltrate in patients with cervical squamous carcinoma is correlated with a worse overall survival, suggesting a less effective immune response in these cases.
Since type 2 cytokines such as IL-4 and IL-5 are known to attract eosinophilic granulocytes, W.J. Vandriel and colleagues from Leiden University, The Netherlands, performed an immunohistochemical study to gain further insight as to whether a type 1 or type 2 immune response is involved in eliciting an eosinophilic...
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