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Tumor Prognostics

"Tumour Vascularity Is a Significant Prognostic Factor for Cervix Carcinoma Treated with Radiotherapy: Independence from Tumour Radiosensitivity."

Published in Cancer Weekly, October 18th, 1999

According to the authors' abstract of an article published in British Journal of Cancer, "The aim of the study was to investigate the relationship between intrinsic radiosensitivity and vascularity in carcinoma of the cervix given radiotherapy, and assess whether more refined prognostic information can be gained by combining the two parameters. A retrospective study was carried out on 74 patients with locally advanced carcinoma of the cervix. Formalin-fixed, paraffin-embedded tumour biopsies were stained with anti-factor VIII using immunohistochemistry. Vascularity was scored using the intra-tumour microvessel density (IMD), or 'hotspot,' technique. For the same patients, the...

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