Cancer Immunotherapy
Antigen-Specific Th1/Th2 Cells Function in Tumor Eradication
Published in Cancer Weekly, October 25th, 1999
T. Nishimura and colleagues from the Hokkaido University, Japan, investigated the role of T helper type 1 (Th1) and Th2 cells in tumor immunity using Th cells induced from ovalbumin (OVA)-specific T-cell receptor transgenic mice. Their results were reported in the Journal of Experimental Medicine ("Distinct Role of Antigen-Specific T Helper Type 1 (Th1) and Th2 Cells in Tumor Eradication in vivo," Journal of Experimental Medicine, September 6, 1999;190(5):617-627).
"Although Th1 cells exhibited stronger cytotoxicity than Th2 cells, both cell types completely...
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Source: Cancer Weekly (1999-10-25)
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