Breast Cancer (Growth Factors)
Growth Factor Is Increased in Certain Breast Cancer Cell Lines
Published in Cancer Weekly, November 1st, 1999
Active angiogenesis is necessary for the progressive growth of hormone-dependent breast cancer, and other malignant tumors. VEGF gene, an important endothelial cell mitogen and an angiogenic agent in tumors, encodes five species of 121, 145, 165, 189, and 206 amino acids (VEGF121-206 ), produced by alternative splicing of VEGF primary mRNA, noted L. Bogin, Weizmann Institute of Science, Rehovot, Israel.
Bogin et al. performed a study to determine whether VEGF alternative...
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Source: Cancer Weekly (1999-11-01)
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