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Neuroblastoma (Genetics)

Search Identifies Chromosome Predisposing Familial NB

Published in Cancer Weekly, November 29th, 1999

A genome-wide search has helped researchers identify a single chromosomal region that may be responsible for predisposing family members to neuroblastoma (NB).

J.M. Maris and colleagues from the Children's Hospital of Philadelphia, Pennsylvania, collected NB families for linkage analysis to determine the genomic location of a NB predisposition gene. The results of their study were presented at the joint meeting of the International Society of Pediatric Oncology, the American Society for Pediatric Hematology/Oncology and the 31st Annual Meeting of the International Society of Pediatric Surgical Oncology, held September 13-18, 1999, in Montreal, Canada.

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