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Bone Marrow Transplantation

Immunosuppression Is Main Cause of Malignant Neoplasms

Published in Cancer Weekly, January 18th, 2000

by Cathy Clark, Senior Editor -- Immunosuppression is the primary cause of malignant neoplasms in patients who receive bone marrow transplantation, according to a research group in Europe.

Bone marrow transplant recipients are at increased risk for new malignant conditions because of several risk factors, including conditioning with radiation and chemotherapy, immune stimulation, and malignant primary disease.

H. J. Kolb of Germany's University of Munich and colleagues performed a retrospective multicenter study to determine the risk and define potential risk factors for new malignant conditions in long-term survivors following bone marrow...

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