Cancer Gene Therapy
Antibody Targeting Facilitates Gene Transfer to RCC Cells
Published in Cancer Weekly, February 1st, 2000
"Specific gene transfer into targeted tumor cells remains a critical issue for the development of systemic gene therapy protocols," stated A. Durrbach and colleagues. "With this end in view, we have tested the possibility of selectively directing genes to tumor cells through the recognition of tumor-associated antigens (TAA)."
Durrbach et al. published the results of their study in Cancer Gene Therapy ("Antibody-mediated endocytosis of G250 tumor-associated antigen allows targeted gene transfer to human renal cell...
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Source: Cancer Weekly (2000-02-01)
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