Antisense Technology
ISIS 5132 Specifically Reduces Target Gene Expression
Published in Cancer Weekly, February 8th, 2000
"Abnormally regulated signaling through proliferative signal transduction pathways characterizes many of the common solid tumors," stated P. J. Odwyer and colleagues from the University of Pennsylvania. "The best described of these involves potentially oncogenic proteins of the Ras family, which activate Raf proteins in the early steps of the mitogen-activated protein kinase cascade."
Odwyer et al. published the results of their study in the journal Clinical Cancer...
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Source: Cancer Weekly (2000-02-08)
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