Bladder Cancer

Eukaryotic Initiation Factor May Have Prognostic Role

Published in Cancer Weekly, February 15th, 2000

Eukaryotic initiation factor-4E may have a role as a prognostic factor in bladder cancer, according to researchers in England.

J. P. Crew and colleagues performed a study to investigate mechanisms regulating VEGF expression in bladder cancer. They published their study in British Journal of Cancer ("Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumor progression," British Journal of Cancer, January 2000;82(1):161-166).

VEGF mRNA and protein were measured in normal bladder (n=12) and primary bladder cancers (n=57). VEGF...

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Source: Cancer Weekly (2000-02-15)

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