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Immunology

Dendritic Cells Vaccine May Spur Tumor Resistance

Published in Cancer Weekly, February 22nd, 2000

A vaccine of tumor peptide-pulsed bone marrow-derived dendritic cells may have promise for inducing tumor resistance.

Grzegorz Dworacki and colleagues evaluated the efficacy of vaccines consisting of tumor peptide-pulsed bone marrow (BM)-derived dendritic cells (DC) generated in the presence of FBS or BALB/c mouse serum (NMS) in the BALB/c Meth A tumor model.

They reported their findings at the Proceedings of the 1999 American Association for Cancer Research-National Cancer Institute-European Organization for Research and Treatment of Cancer New Drugs Meeting, held November 16-19, 1999, in Washington, DC. Their study was titled "Murine non-pulsed...

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