Cancer Gene Therapy

Antisense-Transferrin Receptor Gene Inhibits Breast Cancer

Published in Cancer Weekly, March 14th, 2000

Down-regulation of transferrin receptors inhibits the growth of breast carcinoma cells, reported researchers from the United States.

"The transferrin receptor, a cellular membrane protein, is critical for uptake of iron into cells, and is believed to play a role in cell growth and development," wrote D.C. Yang and colleagues from the Elliot Mastology Center, Louisiana, USA. "We used human breast carcinoma MCF-7 cells as a model system to test this hypothesis."

Yang et al. presented data from their study at the 22nd Annual San Antonio Breast Cancer Symposium. The title of their presentation was "Antisense-transferrin receptor gene inhibits growth of...

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Source: Cancer Weekly (2000-03-14)

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