Colorectal Cancer

Gene Inducing Pituitary Tumors Also Plays Early Role in Colon Cancer Development

Published in Cancer Weekly, March 14th, 2000

A gene that incites the development and growth of pituitary tumors is also expressed in colorectal tumors, pre-cancerous colorectal polyps, and, most abundantly, in invasive colorectal cancer, researchers at Cedars-Sinai Medical Center's Burns & Allen Research Institute reported in The Lancet.

"The novel transforming gene known as Pituitary Tumor Transforming Gene (PTTG1) may prove to be a powerful tool for identifying colon polyps most at risk for becoming malignant and for distinguishing aggressive colorectal cancer, the third leading cause of cancer death in the U.S." said Anthony P. Heaney, MD, lead author.

The discovery may lead to new...

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Source: Cancer Weekly (2000-03-14)

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