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Diagnostics

Voxel Position Affects Brain Tumor Spectroscopy

Published in Cancer Weekly, April 11th, 2000

The accuracy of single-voxel magnetic resonance (MR) spectroscopy in evaluating brain tumors depends on voxel position.

P.E. Ricci and colleagues from the Barrow Neurological Institute reported positioning voxels at the enhancing edge of a tumor produced more accurate spectra concerning lesion histopathology than voxels positioned in the lesion center.

Researchers reviewed 50 single-voxel MR spectra from 43 patients with intra-axial brain tumors. The spectra were acquired using a fully automated stimulated-echo spectroscopy sequence.

Spectra were analyzed for the presence of choline, creatine, N-acetylaspartate (NAA), and...

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