Herpesvirus

Attenuated Virus G207 is Safe in Mice

Published in Cancer Weekly, May 23rd, 2000

Mouse studies show that the attenuated herpes simplex virus type 1 (HSV-1) mutant, G207, is safe at doses that provide effective therapy, according to researchers at Georgetown University in Washington, DC.

This study, conducted by P. Sundaresan and others at the University, was published recently in the Journal of Virology ("Attenuated, replication-competent herpes simplex virus type 1 mutant G207: Safety evaluation in mice," J Virol, 2000;74(8):3832-3841).

Commenting on the study, Sundaresan and colleagues said, "Herpes simplex virus type 1 (HSV-1) mutants that are attenuated for neurovirulence are being used for the treatment of...

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Source: Cancer Weekly (2000-05-23)

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