Published in Cancer Weekly, June 6th, 2000
"Vaccination with cytokine-transduced tumor cells represents a potentially important approach to the treatment of central nervous system tumors," wrote H. Okada and colleagues. "We have recently demonstrated the therapeutic efficacy of tumor cell vaccines expressing the murine IL-4 and the HSV-tk gene in a rat brain tumor model in which nonirradiated vaccine cells can be eliminated by the subsequent administration of ganciclovir.
"In this report, we...
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