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Adverse Drug Effects

Means to Prevent Cardiotoxicity Addressed

Published in Cancer Weekly, June 20th, 2000

Scientists recently concluded that close screening, attention to risk factors, and monitoring for symptoms can prevent cardiotoxicity in patients who have undergone chemotherapy.

V.B. Pai and a colleague from Ohio State University in Columbus, Ohio, discussed the implications of anthracycline cytostatic antibiotics and alkylating agents on the cardiovascular system. Some of the most common chemotherapy treatments, they stated, result in cardiotoxicity. Doxorubicin, danurubicin, and fluorouracil, for instance, may create cardiotoxicity in more than 20% of treated patients. Cardiac complications that may occur at any time after treatment - hours, months, or even years...

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