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Colorectal Cancer

Phase II Trial Data Announced

Published in Cancer Weekly, June 20th, 2000

Xenova Group plc (XNVA; XEN), Slough, United Kingdom, announced trial data for a colorectal study, which is one of four open label Phase II efficacy studies currently being carried out in conjunction with the European Organisation for the Research and Treatment of Cancer (EORTC), on the topoisomerase I and II inhibitor, XR5000.

The purpose of these studies is to investigate the efficacy of XR5000 in a number of different tumor types in order to determine the best course of future clinical development.

Patients received XR5000 at a dose of 3,010 mg/m2 in a 120-hour intravenous infusion every three weeks. Response was assessed following...

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