Immunology

Scientists Discover New Way the Body Distinguishes Self From Foreign

Published in Cancer Weekly, June 27th, 2000

Challenging an important dogma, immunologists have discovered a new way the body distinguishes its cells from foreign cells so it can destroy microbes without harming itself.

The findings suggest a new approach to autoimmune disease and ovarian cancer. They are reported in the June 16 issue of Science.

Like military personnel, cells that kill harmful bacteria and parasites must recognize invaders so they don't destroy their colleagues with friendly fire. Until now, scientists thought that only immune cells called natural killer cells were equipped for the job. These cells scan other cells for a security badge called MHC class I. If this...

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Source: Cancer Weekly (2000-06-27)

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