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Cancer Immunotherapy

Many Factors Influence Success of Antibody-Based Immunotherapy

Published in Cancer Weekly, July 4th, 2000

Two factors are extremely important for determining the potential efficacy of antibody-based cancer immunotherapy, according to AltraRex Corp. researchers:

  • The xenotypic nature of the antibody (tumor-associated antigen-specific antibody originates from a different species than the host), and

  • Existence of a certain level of the circulating specific antigen that complexes with the administered antibody

    "Many mechanisms are involved in tumor-associated antigen (TAA)-specific antibody-based immunotherapy of cancer depending on the nature and specificity of the antibody," said Weimin Qi and colleagues AltaRex Corporation, Massachusetts, reporting at...

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