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Salivary Glands

Breakthroughs in Gene Therapy and Tissue Engineering Reported

Published in Cancer Weekly, July 4th, 2000

The use of gene-transfer technology to repair salivary-gland tissue, allowing a pathway for saliva to flow, in patients undergoing radiation therapy for head and neck cancer, is possible in principle, according to Bruce J. Baum, DMD, PhD.

Baum, who is chief of the Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, U.S. National Institutes of Health, Bethesda, Maryland, spoke about the at the American Dental Association's National Media Conference, held June 15.

"We hypothesized that the major impediment to saliva flow from these irradiated, non-secreting cells was the absence of a pathway for water in their...

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