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Drug Resistance

Ramoplanin Study to Prevent Infection Due to Vancomycin-Resistant Enterococcus Begins Enrollment

Published in Cancer Weekly, July 25th, 2000

IntraBiotics Pharmaceuticals, Inc. (IBPI), Mountain View, California, said that it has begun patient enrollment for the Phase III clinical trial for Ramoplanin Oral.

The trial is designed to demonstrate whether treatment with Ramoplanin reduces the incidence of bloodstream infections due to Vancomycin-Resistant Enterococcus (VRE) in cancer patients known to carry VRE bacteria in their intestines.

The Ramoplanin trial is IntraBiotics' second Phase III clinical trial initiated this year. On May 4, 2000, the company announced it had begun a Phase III trial for its Protegrin IB-367 Oral Rinse, an antibiotic intended to reduce the severity of oral...

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