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Breast Cancer

Sentinel Lymph Node Biopsy Useful Before Neoadjuvant Chemotherapy

Published in Cancer Weekly, July 25th, 2000

University of Pennsylvania researchers recommend that the sentinel lymph node (SLN) biopsy should be used on some patients who will be undergoing neoadjuvant biopsy.

They base this on the results of a study conducted on 103 women at the University of Pennsylvania and the Mayo Clinic.

"Patients with large breast tumors are increasingly undergoing neoadjuvant treatment to downstage local disease: however, accurate staging of the axilla before the initiation of chemotherapy remains problematic," I. Bedrosian and others in the Department of Surgery wrote in the journal Cancer ("Accuracy of sentinel lymph node biopsy in patients with large...

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