Non-Hodgkin's Lymphoma
p53 Gene Mutations Occur Early in AIDS-Associated Disorder
Published in Cancer Weekly, August 29th, 2000
"Chromosomal aberrations are a common feature of lymphomas associated with HIV infection," reported A. Reddy and colleagues from the University of Edinburgh, Scotland, and the University College London Hospital, England. "AIDS-NHL develops in around 5%-10% of HIV infected individuals and involves deregulation of proto-oncogenes such as c-myc, bcl-2, bcl-6, and ras, as well as functional inactivation of tumor suppressor genes, p53 and p16.
"Although the contribution...
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Source: Cancer Weekly (2000-08-29)
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