Colorectal Cancer

Protein Inhibits Growth

Published in Cancer Weekly, September 5th, 2000

University of Toronto researchers have discovered a protein that suppresses colorectal cancer in mice and human cell cultures.

They reported their study in the August 24, 2000 issue of Nature.

The researchers found that if the protein, called p110g, is absent it can cause spontaneous development of colorectal cancer in mice, and when it is present it stops tumor growth. It was a surprise discovery because they were examining how p110g regulates the movement of white blood cells in the immune system, not how it affects cancer cells.

"This is a completely novel and unexpected finding. It defines an entirely new field of...

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Source: Cancer Weekly (2000-09-05)

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