Cancer Vaccines

First Potential 'Universal' Vaccine Shows Promise in Lab

Published in Cancer Weekly, September 12th, 2000

Results from preliminary laboratory studies provide the first functional evidence that developing a "universal" cancer vaccine might be possible, researchers from Duke University Medical Center and Geron Corp. reported.

The scientists found that the active part of telomerase, a protein expressed in all major human cancers, can stimulate development of immune cells when used as the basis for a cancer vaccine. Furthermore, these immune cells can kill multiple, unrelated mouse and human cancer cells in the test tube and can also slow tumor growth in mice.

While not as effective as vaccines based on a tumor's entire genetic material, the promising...

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Source: Cancer Weekly (2000-09-12)

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