Breast Cancer
Select Enzyme Receptors Correlate with Cancer Invasion, Not Progression
Published in Cancer Weekly, October 24th, 2000
Proteolytic enzyme activation during cancer invasion typically involves the destruction of matrices that surround cells. Enzyme specific receptors enable that destruction.
Specific receptors called urokinase-type plasminogen activator receptors (uPAR) are involved in proteolytic activity. Urokinase-type plasminogen activator (UPA) and plasminogen activator inhibitor-1 (PAI-1) are two of the key players in proteolytic enzyme systems that...
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Source: Cancer Weekly (2000-10-24)
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