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Leukemia

Aggressive Treatment Offers Striking Improvement in Infants with Acute Disease

Published in Cancer Weekly, November 7th, 2000

Infants with acute leukemia do not have as favorable a prognosis with conventional chemotherapy as older children. A study suggests that high-dose chemotherapy (HDC) with stem cell transplantation can significantly reduce relapse and improve survival in infants with acute leukemia.

The research was reported in the Journal of Clinical Oncology.

In the past, physicians have relied on traditional doses of chemotherapy to treat infants afflicted with leukemia, prescribing HDC to very few of them because of fear of toxicity. But the new study, the largest of its kind, concluded that HDC is safe and beneficial if offered within four months of a...

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