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Brain Metastases

Promising Results Reported from Xcytrin Phase III Trial for Brain Tumors

Published in Cancer Weekly, November 7th, 2000

Pharmacyclics, Inc. (PCYC) reported results from the lead-in phase of its ongoing randomized Phase III clinical trial of Xcytrin (motexafin gadolinium) Injection for the treatment of cancer patients with brain metastases.

The company also reported promising preliminary results from an ongoing Phase I safety trial of Xcytrin for treatment of glioblastoma multiforme (i.e., primary brain tumors). These results were presented at the 42nd Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), held in Boston, Massachusetts, during October 2000.

"Xcytrin appeared to improve local control in the brain, with very few patients...

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