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Breast Cancer

Radiation Safe and Effective for Patients with BRCA1 or BRCA2 Mutations

Published in Cancer Weekly, November 7th, 2000

To address concerns of patients and physicians, researchers in the United States and Canada examined whether radiation therapy could be safely delivered to women with early stage breast cancer and BRCA1 or BRCA2 genetic mutations - and found that it can.

Some women with these mutations reject radiation therapy in favor of more radical treatments such as mastectomy, because of concerns of the effects of radiotherapy in women who carry a mutation and also of the outcome following treatment.

"Since radiation is known to cause DNA damage, the concern was that the presence of a BRCA1 or BRCA2 breast cancer susceptibility gene would result in a greater...

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